Temsirolimus

In the US, Temsirolimus (temsirolimus systemic) is a member of the drug class mTOR inhibitors and is used to treat Renal Cell Carcinoma.

US matches:

• Temsirolimus


• Temsirolimus Intravenous

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XE09

CAS registry number (Chemical Abstracts Service)

0162635-04-3

Chemical Formula

C56-H87-N-O16

Molecular Weight

1030

Therapeutic Category

Antineoplastic agent, immunosuppressant

Chemical Names

(1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-Dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-ep (WHO)

Rapamycin 42-(2,2-bis(hydroxymethyl)propionate)

Rapamycin, 42-(3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate)

Foreign Names

• Temserolimusum (Latin)
• Temserolimus (German)
• Temsirolimus (French)

Generic Names

• Temsirolimus (OS: BAN, USAN)
• CCl-779 (IS)
• NSC-683864 (IS: WyethAyerst)
• WAY-CCl 779 (IS)

Brand Names

• Torisel
  Pfizer, Switzerland; PharmaSwiss, Croatia (Hrvatska); Wyeth, Austria; Wyeth, Australia; Wyeth, Canada; Wyeth, Germany; Wyeth, Denmark; Wyeth, Spain; Wyeth, Norway; Wyeth, Sweden; Wyeth, Slovenia; Wyeth, Slovakia; Wyeth, United States; Wyeth Pharmaceuticals, United Kingdom

International Drug Name Search

Glossary

BAN	British Approved Name
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.